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Protective Effects of Calpain Inhibition on Neurovascular Unit Injury through Downregulating Nuclear Factor-κB-related Inflammation during Traumatic Brain Injury in Mice

BACKGROUND: In addition to neurons, all components of the neurovascular unit (NVU), such as glial, endothelial, and basal membranes, are destroyed during traumatic brain injury (TBI). Previous studies have shown that excessive stimulation of calpain is crucial for cerebral injury after traumatic ins...

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Detalles Bibliográficos
Autores principales: Tao, Xiao-Gang, Shi, Jing-Hua, Hao, Shu-Yu, Chen, Xue-Tao, Liu, Bai-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282676/
https://www.ncbi.nlm.nih.gov/pubmed/28091411
http://dx.doi.org/10.4103/0366-6999.198001