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Protective Effects of Calpain Inhibition on Neurovascular Unit Injury through Downregulating Nuclear Factor-κB-related Inflammation during Traumatic Brain Injury in Mice
BACKGROUND: In addition to neurons, all components of the neurovascular unit (NVU), such as glial, endothelial, and basal membranes, are destroyed during traumatic brain injury (TBI). Previous studies have shown that excessive stimulation of calpain is crucial for cerebral injury after traumatic ins...
Autores principales: | Tao, Xiao-Gang, Shi, Jing-Hua, Hao, Shu-Yu, Chen, Xue-Tao, Liu, Bai-Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282676/ https://www.ncbi.nlm.nih.gov/pubmed/28091411 http://dx.doi.org/10.4103/0366-6999.198001 |
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