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Efficient estimation of the maximum metabolic productivity of batch systems

BACKGROUND: Production of chemicals from engineered organisms in a batch culture involves an inherent trade-off between productivity, yield, and titer. Existing strategies for strain design typically focus on designing mutations that achieve the highest yield possible while maintaining growth viabil...

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Detalles Bibliográficos
Autores principales: St. John, Peter C., Crowley, Michael F., Bomble, Yannick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282707/
https://www.ncbi.nlm.nih.gov/pubmed/28163785
http://dx.doi.org/10.1186/s13068-017-0709-0