Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania

BACKGROUND: 5-Hydroxymethyluracil (5hmU) is a thymine base modification found in the genomes of a diverse range of organisms. To explore the functional importance of 5hmU, we develop a method for the genome-wide mapping of 5hmU-modified loci based on a chemical tagging strategy for the hydroxymethyl...

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Detalles Bibliográficos
Autores principales: Kawasaki, Fumiko, Beraldi, Dario, Hardisty, Robyn E., McInroy, Gordon R., van Delft, Pieter, Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282726/
https://www.ncbi.nlm.nih.gov/pubmed/28137275
http://dx.doi.org/10.1186/s13059-017-1150-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282726/
https://www.ncbi.nlm.nih.gov/pubmed/28137275
http://dx.doi.org/10.1186/s13059-017-1150-1

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