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Targeting CD133 improves chemotherapeutic efficacy of recurrent pediatric pilocytic astrocytoma following prolonged chemotherapy

BACKGROUND: Pilocytic astrocytomas (PAs) are the most common pediatric central nervous system neoplasms. In the majority of cases these tumors are benign and receive favorable prognosis following gross total surgical resection. In patients with progressive or symptomatic tumors, aggressive surgical...

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Detalles Bibliográficos
Autores principales: Xi, Guifa, Li, Yuping Derek, Grahovac, Gordan, Rajaram, Veena, Wadhwani, Nitin, Pundy, Tatiana, Mania-Farnell, Barbara, James, Charles David, Tomita, Tadanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282778/
https://www.ncbi.nlm.nih.gov/pubmed/28137267
http://dx.doi.org/10.1186/s12943-017-0593-z