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Epigenetics of oropharyngeal squamous cell carcinoma: opportunities for novel chemotherapeutic targets
Epigenetic modifications are heritable changes in gene expression that do not directly alter DNA sequence. These modifications include DNA methylation, histone post-translational modifications, small and non-coding RNAs. Alterations in epigenetic profiles cause deregulation of fundamental gene expre...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282807/ https://www.ncbi.nlm.nih.gov/pubmed/28143553 http://dx.doi.org/10.1186/s40463-017-0185-3 |