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Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms

BACKGROUND: The CRASH-2 trial showed that tranexamic acid (TXA) administration reduces mortality in bleeding trauma patients. However, the effect appeared to depend on how soon after injury TXA treatment was started. Treatment within 3 h reduced bleeding deaths whereas treatment after 3 h increased...

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Detalles Bibliográficos
Autores principales: Roberts, Ian, Edwards, Phil, Prieto, David, Joshi, Miland, Mahmood, Abda, Ker, Katharine, Shakur, Haleema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282847/
https://www.ncbi.nlm.nih.gov/pubmed/28143564
http://dx.doi.org/10.1186/s13063-016-1750-1