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Towards standardization of next-generation sequencing of FFPE samples for clinical oncology: intrinsic obstacles and possible solutions

BACKGROUND: Next generation sequencing has a potential to revolutionize the management of cancer patients within the framework of precision oncology. Nevertheless, lack of standardization decelerated entering of the technology into the clinical testing space. Here we dissected a number of common pro...

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Detalles Bibliográficos
Autores principales: Ivanov, Maxim, Laktionov, Konstantin, Breder, Valery, Chernenko, Polina, Novikova, Ekaterina, Telysheva, Ekaterina, Musienko, Sergey, Baranova, Ancha, Mileyko, Vladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282851/
https://www.ncbi.nlm.nih.gov/pubmed/28137276
http://dx.doi.org/10.1186/s12967-017-1125-8