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Up-regulated NRIP2 in colorectal cancer initiating cells modulates the Wnt pathway by targeting RORβ

BACKGROUND: Colorectal cancer remains one of the most common malignant tumors worldwide. Colorectal cancer initiating cells (CCICs) are a small subpopulation responsible for malignant behaviors of colorectal cancer. Aberrant activation of the Wnt pathways regulates the self-renewal of CCIC. However,...

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Detalles Bibliográficos
Autores principales: Wen, Zhenzhen, Pan, Tianhui, Yang, Saisai, Liu, Jingwen, Tao, Haiying, Zhao, Yiming, Xu, Dingting, Shao, Wei, Wu, Jia, Liu, Xiyong, Wang, Yongjiang, Mao, Jianshan, Zhu, Yongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282884/
https://www.ncbi.nlm.nih.gov/pubmed/28137278
http://dx.doi.org/10.1186/s12943-017-0590-2