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Interplay between CCR7 and Notch1 axes promotes stemness in MMTV-PyMT mammary cancer cells

BACKGROUND: Breast cancer is the major cause of cancer-related mortality in women. It is thought that quiescent stem-like cells within solid tumors are responsible for cancer maintenance, progression and eventual metastasis. We recently reported that the chemokine receptor CCR7, a multi-functional r...

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Detalles Bibliográficos
Autores principales: Boyle, Sarah T., Gieniec, Krystyna A., Gregor, Carly E., Faulkner, Jessica W., McColl, Shaun R., Kochetkova, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282896/
https://www.ncbi.nlm.nih.gov/pubmed/28137279
http://dx.doi.org/10.1186/s12943-017-0592-0