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Interplay between CCR7 and Notch1 axes promotes stemness in MMTV-PyMT mammary cancer cells
BACKGROUND: Breast cancer is the major cause of cancer-related mortality in women. It is thought that quiescent stem-like cells within solid tumors are responsible for cancer maintenance, progression and eventual metastasis. We recently reported that the chemokine receptor CCR7, a multi-functional r...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282896/ https://www.ncbi.nlm.nih.gov/pubmed/28137279 http://dx.doi.org/10.1186/s12943-017-0592-0 |