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Fatty acid binding profile of the liver X receptor α

Liver X receptor (LXR)α is a nuclear receptor that responds to oxysterols and cholesterol overload by stimulating cholesterol efflux, transport, conversion to bile acids, and excretion. LXRα binds to and is regulated by synthetic (T-0901317, GW3695) and endogenous (oxysterols) ligands. LXRα activity...

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Detalles Bibliográficos
Autores principales: Bedi, Shimpi, Hines, Genesis Victoria, Lozada-Fernandez, Valery V., de Jesus Piva, Camila, Kaliappan, Alagammai, Rider, S. Dean, Hostetler, Heather A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282955/
https://www.ncbi.nlm.nih.gov/pubmed/28011707
http://dx.doi.org/10.1194/jlr.M072447