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Fatty acid binding profile of the liver X receptor α
Liver X receptor (LXR)α is a nuclear receptor that responds to oxysterols and cholesterol overload by stimulating cholesterol efflux, transport, conversion to bile acids, and excretion. LXRα binds to and is regulated by synthetic (T-0901317, GW3695) and endogenous (oxysterols) ligands. LXRα activity...
Autores principales: | Bedi, Shimpi, Hines, Genesis Victoria, Lozada-Fernandez, Valery V., de Jesus Piva, Camila, Kaliappan, Alagammai, Rider, S. Dean, Hostetler, Heather A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282955/ https://www.ncbi.nlm.nih.gov/pubmed/28011707 http://dx.doi.org/10.1194/jlr.M072447 |
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