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Regulatory Roles of Anoctamin-6 in Human Trabecular Meshwork Cells
PURPOSE: Trabecular meshwork (TM) cell volume is a determinant of aqueous humor outflow resistance, and thereby IOP. Regulation of TM cell volume depends on chloride ion (Cl(−)) release through swelling-activated channels (I(Cl,Swell)), whose pore is formed by LRRC8 proteins. Chloride ion release th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283088/ https://www.ncbi.nlm.nih.gov/pubmed/28125837 http://dx.doi.org/10.1167/iovs.16-20188 |