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Regulatory Roles of Anoctamin-6 in Human Trabecular Meshwork Cells

PURPOSE: Trabecular meshwork (TM) cell volume is a determinant of aqueous humor outflow resistance, and thereby IOP. Regulation of TM cell volume depends on chloride ion (Cl(−)) release through swelling-activated channels (I(Cl,Swell)), whose pore is formed by LRRC8 proteins. Chloride ion release th...

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Detalles Bibliográficos
Autores principales:	Banerjee, Juni, Leung, Chi-Ting, Li, Ang, Peterson-Yantorno, Kim, Ouyang, Huan, Stamer, W. Daniel, Civan, Mortimer M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2017
Materias:	Physiology and Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283088/ https://www.ncbi.nlm.nih.gov/pubmed/28125837 http://dx.doi.org/10.1167/iovs.16-20188

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