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Immunological mechanisms of intravesical chitosan/interleukin-12 immunotherapy against murine bladder cancer

There is a critical unmet clinical need for bladder cancer immunotherapies capable of inducing durable antitumor immunity. We have shown that four intravesical treatments with a simple co-formulation of interleukin-12 and the biopolymer chitosan not only destroy orthotopic bladder tumors, but also p...

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Detalles Bibliográficos
Autores principales: Smith, Sean G., Baltz, John L., Koppolu, Bhanu Prasanth, Ravindranathan, Sruthi, Nguyen, Khue, Zaharoff, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283638/
https://www.ncbi.nlm.nih.gov/pubmed/28197381
http://dx.doi.org/10.1080/2162402X.2016.1259050