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Immunological mechanisms of intravesical chitosan/interleukin-12 immunotherapy against murine bladder cancer
There is a critical unmet clinical need for bladder cancer immunotherapies capable of inducing durable antitumor immunity. We have shown that four intravesical treatments with a simple co-formulation of interleukin-12 and the biopolymer chitosan not only destroy orthotopic bladder tumors, but also p...
Autores principales: | Smith, Sean G., Baltz, John L., Koppolu, Bhanu Prasanth, Ravindranathan, Sruthi, Nguyen, Khue, Zaharoff, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283638/ https://www.ncbi.nlm.nih.gov/pubmed/28197381 http://dx.doi.org/10.1080/2162402X.2016.1259050 |
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