The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome

Targeting immunomodulatory pathways has ushered a new era in lung cancer therapy. Further progress requires deeper insights into the biology of immune cells in the lung cancer micro-environment. Dendritic cells (DCs) represent a heterogeneous and highly plastic immune cell system with a central role...

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Detalles Bibliográficos
Autores principales: Pyfferoen, Lotte, Brabants, Elisabeth, Everaert, Celine, De Cabooter, Nancy, Heyns, Kelly, Deswarte, Kim, Vanheerswynghels, Manon, De Prijck, Sofie, Waegemans, Glenn, Dullaers, Melissa, Hammad, Hamida, De Wever, Olivier, Mestdagh, Pieter, Vandesompele, Jo, Lambrecht, Bart N., Vermaelen, Karim Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283643/
https://www.ncbi.nlm.nih.gov/pubmed/28197369
http://dx.doi.org/10.1080/2162402X.2016.1253655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283643/
https://www.ncbi.nlm.nih.gov/pubmed/28197369
http://dx.doi.org/10.1080/2162402X.2016.1253655

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