Determination of plasma concentrations of levofloxacin by high performance liquid chromatography for use at a multidrug-resistant tuberculosis hospital in Tanzania

Therapeutic drug monitoring may improve multidrug-resistant tuberculosis (MDR-TB) treatment outcomes. Levofloxacin demonstrates significant individual pharmacokinetic variability. Thus, we sought to develop and validate a high-performance liquid chromatography (HPLC) method with ultraviolet (UV) det...

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Detalles Bibliográficos
Autores principales: Ebers, Andrew, Stroup, Suzanne, Mpagama, Stellah, Kisonga, Riziki, Lekule, Isaack, Liu, Jie, Heysell, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283651/
https://www.ncbi.nlm.nih.gov/pubmed/28141813
http://dx.doi.org/10.1371/journal.pone.0170663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283651/
https://www.ncbi.nlm.nih.gov/pubmed/28141813
http://dx.doi.org/10.1371/journal.pone.0170663

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