Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis

BACKGROUND: KRAS is the most frequently mutated gene in pancreatic ductal adenocarcinoma (PDAC), but the mechanisms underlying the transcriptional response to oncogenic KRAS are still not fully understood. We aimed to uncover transcription factors that regulate the transcriptional response of oncoge...

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Detalles Bibliográficos
Autores principales: Sivakumar, Shivan, de Santiago, Ines, Chlon, Leon, Markowetz, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283690/
https://www.ncbi.nlm.nih.gov/pubmed/28141826
http://dx.doi.org/10.1371/journal.pmed.1002223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283690/
https://www.ncbi.nlm.nih.gov/pubmed/28141826
http://dx.doi.org/10.1371/journal.pmed.1002223

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