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Altered expression of G1/S phase cell cycle regulators in placental mesenchymal stromal cells derived from preeclamptic pregnancies with fetal-placental compromise

Herein, we evaluated whether Placental Mesenchymal Stromal Cells (PDMSCs) derived from normal and Preeclamptic (PE) placentae presented differences in the expression of G1/S-phase regulators p16(INK4A), p18(INK4C), CDK4 and CDK6. Finally, we investigated normal and PE-PDMSCs paracrine effects on Jun...

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Detalles Bibliográficos
Autores principales: Nuzzo, Anna Maria, Giuffrida, Domenica, Masturzo, Bianca, Mele, Paolo, Piccoli, Ettore, Eva, Carola, Todros, Tullia, Rolfo, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283823/
https://www.ncbi.nlm.nih.gov/pubmed/27937072
http://dx.doi.org/10.1080/15384101.2016.1261766