Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

Pharmacological targeting of transcription factors holds great promise for the development of new therapeutics, but strategies based on blockade of DNA binding, nuclear shuttling, or individual protein partner recruitment have yielded limited success to date. Transcription factors typically engage i...

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Detalles Bibliográficos
Autores principales: Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril AB, Holmes, Kelly, Salim, Angela A, Mamidyala, Sreeman, Butler, Mark S, Robinson, Ashley S, Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L, Hogan, Benjamin M, De Val, Sarah, Capon, Robert J, Carroll, Jason S, Bailey, Timothy L, Koopman, Peter, Jauch, Ralf, Cooper, Matthew A, Gambin, Yann, Francois, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283831/
https://www.ncbi.nlm.nih.gov/pubmed/28137359
http://dx.doi.org/10.7554/eLife.21221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283831/
https://www.ncbi.nlm.nih.gov/pubmed/28137359
http://dx.doi.org/10.7554/eLife.21221

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