TCR repertoire sequencing identifies synovial Treg cell clonotypes in the bloodstream during active inflammation in human arthritis

OBJECTIVES: The imbalance between effector and regulatory T (Treg) cells is crucial in the pathogenesis of autoimmune arthritis. Immune responses are often investigated in the blood because of its accessibility, but circulating lymphocytes are not representative of those found in inflamed tissues. T...

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Detalles Bibliográficos
Autores principales: Rossetti, Maura, Spreafico, Roberto, Consolaro, Alessandro, Leong, Jing Yao, Chua, Camillus, Massa, Margherita, Saidin, Suzan, Magni-Manzoni, Silvia, Arkachaisri, Thaschawee, Wallace, Carol A, Gattorno, Marco, Martini, Alberto, Lovell, Daniel J, Albani, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5284348/
https://www.ncbi.nlm.nih.gov/pubmed/27311837
http://dx.doi.org/10.1136/annrheumdis-2015-208992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5284348/
https://www.ncbi.nlm.nih.gov/pubmed/27311837
http://dx.doi.org/10.1136/annrheumdis-2015-208992

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