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Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction

OBJECTIVE: The basic leucine zipper transcription factor, ATF-like (BATF), a member of the Activator protein-1 family, promotes transcriptional activation or repression, depending on the interacting partners (JUN-B or C-JUN). Here, we investigated whether the BATF/JUN complex exerts regulatory effec...

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Detalles Bibliográficos
Autores principales: Rhee, Jinseol, Park, Seo-Hee, Kim, Seul-Ki, Kim, Jin-Hong, Ha, Chul-Won, Chun, Churl-Hong, Chun, Jang-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5284350/
https://www.ncbi.nlm.nih.gov/pubmed/27147707
http://dx.doi.org/10.1136/annrheumdis-2015-208953