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Dynamics of BAF- Polycomb Complex Opposition on Heterochromatin in Normal and Oncogenic States
The opposition between polycomb repressive complexes (PRC) and BAF (mSWI/SNF) complexes plays critical roles in development and disease. Mutations in the genes encoding BAF subunits contribute to over 20% of human malignancy, yet the underlying mechanisms remain unclear owing largely to a lack of as...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285326/ https://www.ncbi.nlm.nih.gov/pubmed/27941796 http://dx.doi.org/10.1038/ng.3734 |