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Dynamics of BAF- Polycomb Complex Opposition on Heterochromatin in Normal and Oncogenic States

The opposition between polycomb repressive complexes (PRC) and BAF (mSWI/SNF) complexes plays critical roles in development and disease. Mutations in the genes encoding BAF subunits contribute to over 20% of human malignancy, yet the underlying mechanisms remain unclear owing largely to a lack of as...

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Detalles Bibliográficos
Autores principales:	Kadoch, Cigall, Williams, Robert T., Calarco, Joseph P., Miller, Erik L., Weber, Christopher M., Braun, Simon G., Pulice, John L., Chory, Emma J., Crabtree, Gerald R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285326/ https://www.ncbi.nlm.nih.gov/pubmed/27941796 http://dx.doi.org/10.1038/ng.3734

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