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The Major Immediate-Early Protein IE2 of Human Cytomegalovirus Is Sufficient to Induce Proteasomal Degradation of CD83 on Mature Dendritic Cells

Human cytomegalovirus (HCMV) is the prototypic beta-herpesvirus and widespread throughout the human population. While infection is asymptomatic in healthy individuals, it can lead to high morbidity and mortality in immunocompromised persons. Importantly, HCMV evolved multiple strategies to interfere...

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Detalles Bibliográficos
Autores principales: Heilingloh, Christiane S., Grosche, Linda, Kummer, Mirko, Mühl-Zürbes, Petra, Kamm, Lisa, Scherer, Myriam, Latzko, Melanie, Stamminger, Thomas, Steinkasserer, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285329/
https://www.ncbi.nlm.nih.gov/pubmed/28203230
http://dx.doi.org/10.3389/fmicb.2017.00119