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Sublingual Priming with a HIV gp41-Based Subunit Vaccine Elicits Mucosal Antibodies and Persistent B Memory Responses in Non-Human Primates

Persistent B cell responses in mucosal tissues are crucial to control infection against sexually transmitted pathogens like human immunodeficiency virus 1 (HIV-1). The genital tract is a major site of infection by HIV. Sublingual (SL) immunization in mice was previously shown to generate HIV-specifi...

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Detalles Bibliográficos
Autores principales: Bekri, Selma, Bourdely, Pierre, Luci, Carmelo, Dereuddre-Bosquet, Nathalie, Su, Bin, Martinon, Frédéric, Braud, Véronique M., Luque, Irene, Mateo, Pedro L., Crespillo, Sara, Conejero-Lara, Francisco, Moog, Christiane, Le Grand, Roger, Anjuère, Fabienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285372/
https://www.ncbi.nlm.nih.gov/pubmed/28203239
http://dx.doi.org/10.3389/fimmu.2017.00063