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Ex vivo rabbit and human corneas as models for bacterial and fungal keratitis

PURPOSE: In the study of microbial keratitis, in vivo animal models often require a large number of animals, and in vitro monolayer cell culture does not maintain the three-dimensional structure of the tissues or cell-to-cell communication of in vivo models. Here, we propose reproducible ex vivo mod...

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Detalles Bibliográficos
Autores principales: Pinnock, Abigail, Shivshetty, Nagaveni, Roy, Sanhita, Rimmer, Stephen, Douglas, Ian, MacNeil, Sheila, Garg, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285415/
https://www.ncbi.nlm.nih.gov/pubmed/27844206
http://dx.doi.org/10.1007/s00417-016-3546-0