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Dietary cholesterol promotes repair of demyelinated lesions in the adult brain

Multiple Sclerosis (MS) is an inflammatory demyelinating disorder in which remyelination failure contributes to persistent disability. Cholesterol is rate-limiting for myelin biogenesis in the developing CNS; however, whether cholesterol insufficiency contributes to remyelination failure in MS, is u...

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Detalles Bibliográficos
Autores principales: Berghoff, Stefan A., Gerndt, Nina, Winchenbach, Jan, Stumpf, Sina K., Hosang, Leon, Odoardi, Francesca, Ruhwedel, Torben, Böhler, Carolin, Barrette, Benoit, Stassart, Ruth, Liebetanz, David, Dibaj, Payam, Möbius, Wiebke, Edgar, Julia M., Saher, Gesine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286209/
https://www.ncbi.nlm.nih.gov/pubmed/28117328
http://dx.doi.org/10.1038/ncomms14241