HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation

Cancer genome sequencing projects have identified hundreds of genetic alterations, often at low frequencies, raising questions as to their functional relevance. One exemplar gene is HUWE1, which has been found to be mutated in numerous studies. However, due to the large size of this gene and a lack...

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Detalles Bibliográficos
Autores principales: Myant, Kevin B, Cammareri, Patrizia, Hodder, Michael C, Wills, Jimi, Von Kriegsheim, Alex, Győrffy, Balázs, Rashid, Mamun, Polo, Simona, Maspero, Elena, Vaughan, Lynsey, Gurung, Basanta, Barry, Evan, Malliri, Angeliki, Camargo, Fernando, Adams, David J, Iavarone, Antonio, Lasorella, Anna, Sansom, Owen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286368/
https://www.ncbi.nlm.nih.gov/pubmed/28003334
http://dx.doi.org/10.15252/emmm.201606684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286368/
https://www.ncbi.nlm.nih.gov/pubmed/28003334
http://dx.doi.org/10.15252/emmm.201606684

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