ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth

Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer death; identifying PDAC enablers may reveal potential therapeutic targets. Expression of the actomyosin regulatory ROCK1 and ROCK2 kinases increased with tumor progression in human and mouse pancreatic tumors, while elevated ROCK1/RO...

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Detalles Bibliográficos
Autores principales: Rath, Nicola, Morton, Jennifer P, Julian, Linda, Helbig, Lena, Kadir, Shereen, McGhee, Ewan J, Anderson, Kurt I, Kalna, Gabriela, Mullin, Margaret, Pinho, Andreia V, Rooman, Ilse, Samuel, Michael S, Olson, Michael F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286371/
https://www.ncbi.nlm.nih.gov/pubmed/28031255
http://dx.doi.org/10.15252/emmm.201606743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286371/
https://www.ncbi.nlm.nih.gov/pubmed/28031255
http://dx.doi.org/10.15252/emmm.201606743

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