Cargando…

ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth

Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer death; identifying PDAC enablers may reveal potential therapeutic targets. Expression of the actomyosin regulatory ROCK1 and ROCK2 kinases increased with tumor progression in human and mouse pancreatic tumors, while elevated ROCK1/RO...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rath, Nicola, Morton, Jennifer P, Julian, Linda, Helbig, Lena, Kadir, Shereen, McGhee, Ewan J, Anderson, Kurt I, Kalna, Gabriela, Mullin, Margaret, Pinho, Andreia V, Rooman, Ilse, Samuel, Michael S, Olson, Michael F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286371/ https://www.ncbi.nlm.nih.gov/pubmed/28031255 http://dx.doi.org/10.15252/emmm.201606743

Ejemplares similares

ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells
por: Rath, Nicola, et al.
Publicado: (2016)

Immunogenic Death of Hepatocellular Carcinoma Cells in Mice Expressing Caspase-Resistant ROCK1 Is Not Replicated by ROCK Inhibitors
por: Naylor, Gregory, et al.
Publicado: (2022)

High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium
por: Huo, Cecilia W., et al.
Publicado: (2015)

Monitoring the dynamics of Src activity in response to anti-invasive dasatinib treatment at a subcellular level using dual intravital imaging
por: Nobis, Max, et al.
Publicado: (2014)

Nanoscape, a data-driven 3D real-time interactive virtual cell environment
por: Kadir, Shereen R, et al.
Publicado: (2021)

Metabolism remodeling in pancreatic ductal adenocarcinoma
por: Li, Jin-Tao, et al.
Publicado: (2019)

Sirtainties in pancreatic cancer?
por: Rooman, Ilse
Publicado: (2014)

Abastecimiento de agua y alcantarillado : ingeniería ambiental /
por: McGhee, Terence J.
Publicado: (1999)

THE INFECTION BY PLASMODIUM LOPHURAE OF DUCK ERYTHROCYTES IN THE CHICKEN EMBRYO
por: McGhee, R. Barclay
Publicado: (1953)

Inventario cinco factores de personalidad para niños : FFPI-C /
por: McGhee, Ronnie L.
Publicado: (2019)

Máxima productividad : recupera tu vida usando Microsoft Outlook
por: McGhee, Sally, 1959-
Publicado: (2010)

Polarized Cell Motility Induces Hydrogen Peroxide to Inhibit Cofilin via Cysteine Oxidation
por: Cameron, Jenifer M., et al.
Publicado: (2015)

In Situ Imaging of Tissue Remodeling with Collagen Hybridizing Peptides
por: Hwang, Jeongmin, et al.
Publicado: (2017)

Partial Differential Equations: A unified Hilbert Space Approach
por: Picard, Rainer, et al.
Publicado: (2011)

Sphere-forming cells from peripheral cornea demonstrate the ability to repopulate the ocular surface
por: Mathan, Jeremy John, et al.
Publicado: (2016)

The Rac-FRET Mouse Reveals Tight Spatiotemporal Control of Rac Activity in Primary Cells and Tissues
por: Johnsson, Anna-Karin E., et al.
Publicado: (2014)

Organotypic Collagen I Assay: A Malleable Platform to Assess Cell Behaviour in a 3-Dimensional Context
por: Timpson, Paul, et al.
Publicado: (2011)

FACTORS IN PLASMA CONCERNED IN NATURAL RESISTANCE TO AN AVIAN MALARIA PARASITE (PLASMODIUM LOPHURAE)
por: Trager, William, et al.
Publicado: (1950)

Inside the Mucosal Immune System
por: McGhee, Jerry R., et al.
Publicado: (2012)

Painless project management: a step-by-step guide for planning, executing, and managing projects
por: McGhee, Pamela, et al.
Publicado: (2007)

A cross-sectional study on socioeconomic status and health-related quality of life among elderly Chinese
por: Ma, Xiaoguang, et al.
Publicado: (2013)

Simulation Study of Surface Transfer Doping of Hydrogenated Diamond by MoO(3) and V(2)O(5) Metal Oxides
por: McGhee, Joseph, et al.
Publicado: (2020)

Collagen hydrogel viscoelasticity regulates MSC chondrogenesis in a ROCK-dependent manner
por: Huang, Danyang, et al.
Publicado: (2023)

Increased peri-ductal collagen micro-organization may contribute to raised mammographic density
por: McConnell, James C., et al.
Publicado: (2016)

Erwinia amylovora CRISPR Elements Provide New Tools for Evaluating Strain Diversity and for Microbial Source Tracking
por: McGhee, Gayle C., et al.
Publicado: (2012)

Coevolutionary Constraints? The Environment Alters Tripartite Interaction Traits in a Legume
por: Heath, Katy D., et al.
Publicado: (2012)

DOCK8 Immune Deficiency as a Model for Primary Cytoskeletal Dysfunction
por: McGhee, Sean A., et al.
Publicado: (2010)

Presumed late recurrence of Acanthamoeba keratitis exacerbated by exposure to topical corticosteroids
por: Patel, Dipika V, et al.
Publicado: (2013)

A Technical Point for Split Thickness Skin Graft: This Side Up
por: McGhee, James T., et al.
Publicado: (2019)

Effects of microbial phytase on standardized total tract digestibility of phosphorus in hybrid rye, barley, wheat, corn, and sorghum fed to growing pigs
por: McGhee, Molly L, et al.
Publicado: (2019)

Ongoing debates in endothelial keratoplasty: DMEK is not the new DSAEK!
por: Al-Mahrouqi, Haitham, et al.
Publicado: (2022)

From Preventing physical infection to managing affective contagion: An initial study of daily nursing practices in the early outbreak of the COVID-19 pandemic in Wuhan
por: Wen, Man, et al.
Publicado: (2023)

MRCK: a master regulator of tissue remodeling or another ‘ROCK’ in the epithelial block?
por: Zihni, Ceniz
Publicado: (2021)

Mesenchymal Stem-Cell Remodeling of Adsorbed Type-I Collagen—The Effect of Collagen Oxidation
por: Komsa-Penkova, Regina, et al.
Publicado: (2022)

Pullulan‐Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings
por: Chen, Kellen, et al.
Publicado: (2022)

Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia
por: Pinho, Andreia V., et al.
Publicado: (2015)

Pullulan-Collagen Hydrogel Wound Dressing Promotes Dermal Remodeling and Wound Healing Compared to Commercially Available Collagen Dressings
por: Sivaraj, Dharshan, et al.
Publicado: (2022)

The role of the SWI/SNF chromatin remodeling complex in pancreatic ductal adenocarcinoma
por: Tsuda, Motoyuki, et al.
Publicado: (2020)

Monocarboxylate Transporters Are Involved in Extracellular Matrix Remodelling in Pancreatic Ductal Adenocarcinoma
por: Ufuk, Ayşe, et al.
Publicado: (2022)

Exploring new uses for existing drugs: innovative mechanisms to fund independent clinical research
por: Verbaanderd, Ciska, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5bc4nqeqqakemttj26nopm39d7