PD‐L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy

Pancreatic ductal adenocarcinoma (PDAC) is considered a non‐immunogenic tumor, and immune checkpoint inhibitor monotherapy lacks efficacy in this disease. Radiotherapy (RT) can stimulate the immune system. Here, we show that treatment of KPC and Pan02 murine PDAC cells with RT and gemcitabine upregu...

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Detalles Bibliográficos
Autores principales: Azad, Abul, Yin Lim, Su, D'Costa, Zenobia, Jones, Keaton, Diana, Angela, Sansom, Owen J, Kruger, Philipp, Liu, Stanley, McKenna, W Gillies, Dushek, Omer, Muschel, Ruth J, Fokas, Emmanouil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286375/
https://www.ncbi.nlm.nih.gov/pubmed/27932443
http://dx.doi.org/10.15252/emmm.201606674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286375/
https://www.ncbi.nlm.nih.gov/pubmed/27932443
http://dx.doi.org/10.15252/emmm.201606674

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