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High-throughput screen detects calcium signaling dysfunction in typical sporadic autism spectrum disorder

Autism spectrum disorder (ASD) is a heterogeneous group of neurodevelopmental disorders without any defined uniting pathophysiology. Ca(2+) signaling is emerging as a potential node in the genetic architecture of the disorder. We previously reported decreased inositol trisphosphate (IP(3))-mediated...

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Detalles Bibliográficos
Autores principales: Schmunk, Galina, Nguyen, Rachel L., Ferguson, David L., Kumar, Kenny, Parker, Ian, Gargus, J. Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286408/
https://www.ncbi.nlm.nih.gov/pubmed/28145469
http://dx.doi.org/10.1038/srep40740