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Autophagic flux, a possible mechanism for delayed gentamicin-induced ototoxicity

Aminoglycoside antibiotics including gentamicin (GM) induce delayed ototoxic effects such as hearing loss after long-term use, unlike the early-onset ototoxicity caused by cisplatin. The purpose of the study was to identify the mechanism of the delayed GM-induced ototoxicity by exploring the role of...

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Detalles Bibliográficos
Autores principales: Kim, Yeon Ju, Tian, Chunjie, Kim, Jangho, Shin, Beomyong, Choo, Oak-Sung, Kim, You-Sun, Choung, Yun-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286410/
https://www.ncbi.nlm.nih.gov/pubmed/28145495
http://dx.doi.org/10.1038/srep41356