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The Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling

L-plastin is a calcium-regulated actin-bundling protein that is expressed in cells of hematopoietic origin and in most metastatic cancer cells. These cell types are mobile and require the constant remodeling of their actin cytoskeleton, where L-plastin bundles filamentous actin. The calcium-dependen...

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Detalles Bibliográficos
Autores principales: Ishida, Hiroaki, Jensen, Katharine V., Woodman, Andrew G., Hyndman, M. Eric, Vogel, Hans J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286426/
https://www.ncbi.nlm.nih.gov/pubmed/28145401
http://dx.doi.org/10.1038/srep40662