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TDAG8 involved in initiating inflammatory hyperalgesia and establishing hyperalgesic priming in mice

Chronic pain, resulting from injury, arthritis, and cancer, is often accompanied by inflammation. High concentrations of protons found in inflamed tissues results in tissue acidosis, a major cause of pain and hyperalgesia. Acidosis signals may mediate a transition from acute to chronic hyperalgesia...

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Detalles Bibliográficos
Autores principales: Dai, Shih-Ping, Huang, Ya-Han, Chang, Chung-Jen, Huang, Yu-Fen, Hsieh, Wei-Shan, Tabata, Yasuhiko, Ishii, Satoshii, Sun, Wei-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286436/
https://www.ncbi.nlm.nih.gov/pubmed/28145512
http://dx.doi.org/10.1038/srep41415