Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects

Hypoadiponectinemia and adiponectin resistance are implicated in the aetiology of obesity-related cardiometabolic disorders, hence represent a potential therapeutic axis. Here we characterised the effects of in vivo electrotransfer-mediated overexpression of the adiponectin receptors, AdipoR1 or Adi...

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Detalles Bibliográficos
Autores principales: Keshvari, Sahar, Henstridge, Darren C., Ng, Choaping, Febbraio, Mark A., Whitehead, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286438/
https://www.ncbi.nlm.nih.gov/pubmed/28145500
http://dx.doi.org/10.1038/srep41792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286438/
https://www.ncbi.nlm.nih.gov/pubmed/28145500
http://dx.doi.org/10.1038/srep41792

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