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Intracellular Accumulation of Gold Nanoparticles Leads to Inhibition of Macropinocytosis to Reduce the Endoplasmic Reticulum Stress

Understanding the toxicity of nanomaterials remains largely limited to acute cellular response, i.e., short-term in vitro cell-death based assays, and analyses of tissue- and organ-level accumulation and clearance patterns in animal models, which have produced very little information about how these...

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Detalles Bibliográficos
Autores principales: Gunduz, Nuray, Ceylan, Hakan, Guler, Mustafa O., Tekinay, Ayse B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286442/
https://www.ncbi.nlm.nih.gov/pubmed/28145529
http://dx.doi.org/10.1038/srep40493