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Imidazoles Induce Reactive Oxygen Species in Mycobacterium tuberculosis Which Is Not Associated with Cell Death

[Image: see text] Azoles are a class of antimicrobial drugs used clinically to treat yeast and fungal infections. Against pathogenic yeast and fungi, azoles act by inhibiting the activity of the cytochrome P450 Cyp51, which is involved in the synthesis of a critical component of the yeast and fungal...

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Detalles Bibliográficos
Autores principales: Howell Wescott, Heather A., Roberts, David M., Allebach, Christian L., Kokoczka, Rachel, Parish, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286457/
https://www.ncbi.nlm.nih.gov/pubmed/28180188
http://dx.doi.org/10.1021/acsomega.6b00212