Synergistic effects of metformin with liraglutide against endothelial dysfunction through GLP-1 receptor and PKA signalling pathway

Metformin or glucagon-like peptide-1 (GLP-1) analogue liraglutide has cardiovascular benefits. However, it is not clear whether their combined treatment have additive or synergistic effects on the vasculature. In this study, human umbilical vein endothelial cells (HUVECs), exposed to palmitic acid (...

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Detalles Bibliográficos
Autores principales: Ke, Jing, Liu, Ye, Yang, Jin, Lu, Ran, Tian, Qing, Hou, Wenfang, Wang, Guang, Wei, Rui, Hong, Tianpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286534/
https://www.ncbi.nlm.nih.gov/pubmed/28145471
http://dx.doi.org/10.1038/srep41085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286534/
https://www.ncbi.nlm.nih.gov/pubmed/28145471
http://dx.doi.org/10.1038/srep41085

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