Cargando…

Upregulation of MiR-205 transcriptionally suppresses SMAD4 and PTEN and contributes to human ovarian cancer progression

MicroRNAs (miRNAs) function as critical regulators of gene expression and their deregulation is associated with the development and progression of various cancers. This study aimed to investigate the biological role and mechanism of miR-205 in ovarian cancer (OC). MiR-205 was upregulated in OC tissu...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Juanni, Hu, Kuan, Gong, Guanghui, Zhu, Ding, Wang, Yixuan, Liu, Hailing, Wu, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286557/
https://www.ncbi.nlm.nih.gov/pubmed/28145479
http://dx.doi.org/10.1038/srep41330