Cargando…

Upregulation of MiR-205 transcriptionally suppresses SMAD4 and PTEN and contributes to human ovarian cancer progression

MicroRNAs (miRNAs) function as critical regulators of gene expression and their deregulation is associated with the development and progression of various cancers. This study aimed to investigate the biological role and mechanism of miR-205 in ovarian cancer (OC). MiR-205 was upregulated in OC tissu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Juanni, Hu, Kuan, Gong, Guanghui, Zhu, Ding, Wang, Yixuan, Liu, Hailing, Wu, Xiaoying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286557/ https://www.ncbi.nlm.nih.gov/pubmed/28145479 http://dx.doi.org/10.1038/srep41330

Ejemplares similares

miR-205 regulates the proliferation and invasion of ovarian cancer cells via suppressing PTEN/SMAD4 expression
por: Chu, Ping, et al.
Publicado: (2018)

Ovarian cancer cell-secreted exosomal miR-205 promotes metastasis by inducing angiogenesis
por: He, Liuqing, et al.
Publicado: (2019)

miR-205-5p Mediated Downregulation of PTEN Contributes to Cisplatin Resistance in C13K Human Ovarian Cancer Cells
por: Shi, Xiaoyan, et al.
Publicado: (2018)

Upregulation of Long Noncoding RNA GAS5 Inhibits Lung Cancer Cell Proliferation and Metastasis via miR-205/PTEN Axis
por: Dong, Lizhen, et al.
Publicado: (2019)

Upregulation of miR-572 transcriptionally suppresses SOCS1 and p21 and contributes to human ovarian cancer progression
por: Zhang, Xin, et al.
Publicado: (2015)

UVB suppresses PTEN expression by upregulating miR-141 in HaCaT cells()
por: Li, Wei, et al.
Publicado: (2011)

Long noncoding RNA MALAT1 promotes cell proliferation through suppressing miR-205 and promoting SMAD4 expression in osteosarcoma
por: Li, Qingbo, et al.
Publicado: (2017)

miR-18a Inhibitor Suppresses Leukemia Cell Proliferation by Upregulation of PTEN Expression
por: Zhang, Liping, et al.
Publicado: (2020)

Suppression of cell growth and invasion by miR-205 in breast cancer
por: Wu, Hailong, et al.
Publicado: (2009)

TGF-β1 regulating miR-205/miR-195 expression affects the TGF-β signal pathway by respectively targeting SMAD2/SMAD7
por: Duan, Yingjun, et al.
Publicado: (2016)

LncRNA DGCR5 plays a tumor-suppressive role in glioma via the miR-21/Smad7 and miR-23a/PTEN axes
por: He, Zongze, et al.
Publicado: (2020)

circPTEN1, a circular RNA generated from PTEN, suppresses cancer progression through inhibition of TGF-β/Smad signaling
por: Zheng, Lin, et al.
Publicado: (2022)

Upregulation Of miR-149-3p Suppresses Spinal Chordoma Malignancy By Targeting Smad3
por: Yao, Jie, et al.
Publicado: (2019)

Unveiling the ups and downs of miR-205 in physiology and cancer: transcriptional and post-transcriptional mechanisms
por: Ferrari, Elena, et al.
Publicado: (2020)

Upregulated GATA3/miR205-5p Axis Inhibits MFNG Transcription and Reduces the Malignancy of Triple-Negative Breast Cancer
por: Mugisha, Samson, et al.
Publicado: (2022)

Upregulation of MiR-205 under hypoxia promotes epithelial–mesenchymal transition by targeting ASPP2
por: Wang, Xingwen, et al.
Publicado: (2016)

MiR-205 mediated APC regulation contributes to pancreatic cancer cell proliferation
por: Qin, Rui-Feng, et al.
Publicado: (2019)

Tumor Suppressive Function of mir-205 in Breast Cancer Is Linked to HMGB3 Regulation
por: Elgamal, Ola A., et al.
Publicado: (2013)

miR-222 promotes invasion and migration of ovarian carcinoma by targeting PTEN
por: Gong, Li, et al.
Publicado: (2018)

Repression of Smad4 by miR-205 moderates TGF-β-induced epithelial-mesenchymal transition in A549 cell lines
por: Zeng, Yuanyuan, et al.
Publicado: (2021)

Arecoline suppresses epithelial cell viability by upregulating tropomyosin-1 through the transforming growth factor-β/Smad pathway
por: Li, Long, et al.
Publicado: (2020)

MiR-186 bidirectionally regulates cisplatin sensitivity of ovarian cancer cells via suppressing targets PIK3R3 and PTEN and upregulating APAF1 expression
por: Xiang, Ying, et al.
Publicado: (2020)

miR-205 Reverses MDR-1 Mediated Doxorubicin Resistance via PTEN in Human Liver Cancer HepG2 Cells
por: Li, Mei, et al.
Publicado: (2022)

HOTTIP-miR-205-ZEB2 Axis Confers Cisplatin Resistance to Ovarian Cancer Cells
por: Dong, Yu-Jie, et al.
Publicado: (2021)

Overexpression of SP1 restores autophagy to alleviate acute renal injury induced by ischemia-reperfusion through the miR-205/PTEN/Akt pathway
por: Huang, Chong, et al.
Publicado: (2021)

Upregulation of miR-382 contributes to renal fibrosis secondary to aristolochic acid-induced kidney injury via PTEN signaling pathway
por: Wang, Xiaoyan, et al.
Publicado: (2020)

Long non-coding RNA CASC2 upregulates PTEN to suppress pancreatic carcinoma cell metastasis by downregulating miR-21
por: Zhang, Hui, et al.
Publicado: (2019)

Prognostic Significance of miR-205 in Endometrial Cancer
por: Karaayvaz, Mihriban, et al.
Publicado: (2012)

miR-205 in Breast Cancer: State of the Art
por: Plantamura, Ilaria, et al.
Publicado: (2020)

miR-205-5p downregulation decreases gemcitabine sensitivity of breast cancer cells via ERp29 upregulation
por: Ma, Changpo, et al.
Publicado: (2019)

Upregulation of Linc00284 Promotes Lung Cancer Progression by Regulating the miR-205-3p/c-Met Axis
por: Sheng, Wang, et al.
Publicado: (2021)

Targeting Gastrin-Releasing Peptide Suppresses Neuroblastoma Progression via Upregulation of PTEN Signaling
por: Paul, Pritha, et al.
Publicado: (2013)

Topical MTII Therapy Suppresses Melanoma Through PTEN Upregulation and Cyclooxygenase II Inhibition
por: Wu, Jian-Ching, et al.
Publicado: (2020)

The effect of androgens on ovarian follicle maturation: Dihydrotestosterone suppress FSH-stimulated granulosa cell proliferation by upregulating PPARγ-dependent PTEN expression.
por: Chen, Mei-Jou, et al.
Publicado: (2015)

Icariin inhibits the malignant progression of lung cancer by affecting the PI3K/Akt pathway through the miR-205-5p/PTEN axis
por: Zhu, Fengjie, et al.
Publicado: (2022)

LncRNA CTBP1-AS2 sponges miR-216a to upregulate PTEN and suppress endometrial cancer cell invasion and migration
por: Wang, Qing-an-zi, et al.
Publicado: (2020)

LncRNA CTBP1-AS2 regulates miR-216a/ PTEN to suppress ovarian cancer cell proliferation
por: Cui, Kaiying, et al.
Publicado: (2020)

LncRNA GAS5 suppresses ovarian cancer progression by targeting the miR-96-5p/PTEN axis
por: Dong, Qian, et al.
Publicado: (2021)

miR-205 suppresses the proliferative and migratory capacity of human osteosarcoma Mg-63 cells by targeting VEGFA
por: Wang, Li, et al.
Publicado: (2015)

Novel Long Noncoding RNA miR205HG Functions as an Esophageal Tumor-Suppressive Hedgehog Inhibitor
por: Song, Jee Hoon, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ojeiss94lo091ifo6rn905pcse