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Escape from IFN-γ-dependent immunosurveillance in tumorigenesis

Immune interferon (IFN), also known as IFN-γ, promotes not only immunomodulation but also antimicrobial and anticancer activity. After IFN-γ binds to the complex of IFN-γ receptor (IFNGR) 1-IFNGR2 and subsequently activates its downstream signaling pathways, IFN-γ immediately causes transcriptional...

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Detalles Bibliográficos
Autores principales: Lin, Chiou-Feng, Lin, Chih-Ming, Lee, Kang-Yun, Wu, Szu-Yuan, Feng, Po-Hao, Chen, Kuan-Yuan, Chuang, Hsiao-Chi, Chen, Chia-Ling, Wang, Yu-Chih, Tseng, Po-Chun, Tsai, Tsung-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286687/
https://www.ncbi.nlm.nih.gov/pubmed/28143527
http://dx.doi.org/10.1186/s12929-017-0317-0