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“HLA-G 3′UTR gene polymorphisms and rheumatic heart disease: a familial study among South Indian population”

BACKGROUND: Rheumatic heart disease (RHD) is an autoimmune disease where cross reactive CD4(+) T cells are involved in the pathogenesis of valvular damage. Human Leukocyte Antigen-G (HLA-G), an immunosuppressive molecule playing a crucial role in the inhibition of T cell response is associated with...

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Detalles Bibliográficos
Autores principales: Poomarimuthu, Maheshkumar, Elango, Sivakumar, Soundrapandian, Sambath, Mariakuttikan, Jayalakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286793/
https://www.ncbi.nlm.nih.gov/pubmed/28143491
http://dx.doi.org/10.1186/s12969-017-0140-x