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Discoidin domain receptor 1 activity drives an aggressive phenotype in gastric carcinoma

BACKGROUND: Discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase that utilizes collagen as a ligand, is a key molecule in the progression of solid tumors as it regulates the interaction of cancer cells with the tumor stroma. However, the clinical relevance of DDR1 expression in gastric car...

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Detalles Bibliográficos
Autores principales: Hur, Hoon, Ham, In-Hye, Lee, Dakeun, Jin, Hyejin, Aguilera, Kristina Y., Oh, Hye Jeong, Han, Sang-Uk, Kwon, Ji Eun, Kim, Young-Bae, Ding, Ke, Brekken, Rolf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286810/
https://www.ncbi.nlm.nih.gov/pubmed/28143619
http://dx.doi.org/10.1186/s12885-017-3051-9