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Discoidin domain receptor 1 activity drives an aggressive phenotype in gastric carcinoma
BACKGROUND: Discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase that utilizes collagen as a ligand, is a key molecule in the progression of solid tumors as it regulates the interaction of cancer cells with the tumor stroma. However, the clinical relevance of DDR1 expression in gastric car...
Autores principales: | Hur, Hoon, Ham, In-Hye, Lee, Dakeun, Jin, Hyejin, Aguilera, Kristina Y., Oh, Hye Jeong, Han, Sang-Uk, Kwon, Ji Eun, Kim, Young-Bae, Ding, Ke, Brekken, Rolf A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286810/ https://www.ncbi.nlm.nih.gov/pubmed/28143619 http://dx.doi.org/10.1186/s12885-017-3051-9 |
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