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Prokaryotic ubiquitin-like protein remains intrinsically disordered when covalently attached to proteasomal target proteins

BACKGROUND: The post-translational modification pathway referred to as pupylation marks proteins for proteasomal degradation in Mycobacterium tuberculosis and other actinobacteria by covalently attaching the small protein Pup (prokaryotic ubiquitin-like protein) to target lysine residues. In contras...

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Detalles Bibliográficos
Autores principales: Barandun, Jonas, Damberger, Fred F., Delley, Cyrille L., Laederach, Juerg, Allain, Frédéric H. T., Weber-Ban, Eilika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286830/
https://www.ncbi.nlm.nih.gov/pubmed/28143508
http://dx.doi.org/10.1186/s12900-017-0072-1