A novel Salmonella strain inactivated by a regulated autolysis system and expressing the B subunit of Shiga toxin 2e efficiently elicits immune responses and confers protection against virulent Stx2e-producing Escherichia coli

BACKGROUND: Salmonella Typhimurium (S. Typhimurium) inactivated by a regulated autolysis system was genetically engineered to express the homo-pentameric B subunit of Shiga toxin 2e (Stx2eB) on its surface. To prepare a strain able to yield autolyzed Salmonella bearing Stx2eB, the plasmid pJHL184 ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Won, Gayeon, Kim, Tae Hoon, Lee, John Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286835/
https://www.ncbi.nlm.nih.gov/pubmed/28143511
http://dx.doi.org/10.1186/s12917-017-0962-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286835/
https://www.ncbi.nlm.nih.gov/pubmed/28143511
http://dx.doi.org/10.1186/s12917-017-0962-2

Ejemplares similares