Cargando…

Current insights into LMNA cardiomyopathies: Existing models and missing LINCs

The nuclear lamina is a critical structural domain for the maintenance of genomic stability and whole-cell mechanics. Mutations in the LMNA gene, which encodes nuclear A-type lamins lead to the disruption of these key cellular functions, resulting in a number of devastating diseases known as laminop...

Descripción completa

Detalles Bibliográficos
Autores principales: Brayson, Daniel, Shanahan, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287098/
https://www.ncbi.nlm.nih.gov/pubmed/28125396
http://dx.doi.org/10.1080/19491034.2016.1260798